반응식
C[O:2][C:3](=[O:33])[C@H:4]([O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][NH:14][C:15]([C:17]2[C:18]([O:23][C:24]3[CH:29]=[CH:28][CH:27]=[C:26]([C:30]#[N:31])[CH:25]=3)=[N:19][CH:20]=[CH:21][CH:22]=2)=[O:16])=[C:9]([F:32])[CH:8]=1)[CH3:5].COC(=O)COC1C=CC(CNC(C2C(OC3C=CC4OCOC=4C=3)=NC=CC=2)=O)=C(F)C=1>>[F:32][C:9]1[CH:8]=[C:7]([CH:12]=[CH:11][C:10]=1[CH2:13][NH:14][C:15]([C:17]1[C:18]([O:23][C:24]2[CH:29]=[CH:28][CH:27]=[C:26]([C:30]#[N:31])[CH:25]=2)=[N:19][CH:20]=[CH:21][CH:22]=1)=[O:16])[O:6][C@H:4]([CH3:5])[C:3]([OH:33])=[O:2]참가 물질
3
반응물 2
생성물 1
실험 절차
The compound of Formula (5.5.11) was prepared in a manner analogous to that described in Example 1, substituting (R)-2-[3-fluoro-4-({[2-(3-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid methyl ester for the corresponding [4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-acetic acid methyl ester material.
출처 및 근거
- ORD 기록
- ord-cc432e0d90b447218218ad80c6e63db2
- 출처 데이터셋
- uspto-grants-2007_02
- 특허 번호
- US07183293B2
연결된 노트
불러오는 중…