반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:11]=[CH:12][C:13]=1[CH2:14][NH:15][C:16]([C:18]1[C:19]([O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([C:31]#[N:32])[CH:26]=2)=[N:20][CH:21]=[CH:22][CH:23]=1)=[O:17])[O:5][C@H:6]([CH3:10])[C:7](O)=[O:8].O1C2C=CC(OC3C(C(NCC4C=CC(O[C@H](C)C(O)=O)=CC=4F)=O)=CC=C[N:44]=3)=CC=2OC1>>[C:7]([C@H:6]([O:5][C:4]1[CH:11]=[CH:12][C:13]([CH2:14][NH:15][C:16](=[O:17])[C:18]2[CH:23]=[CH:22][CH:21]=[N:20][C:19]=2[O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([C:31]#[N:32])[CH:26]=2)=[C:2]([F:1])[CH:3]=1)[CH3:10])(=[O:8])[NH2:44]참가 물질
3
실험 절차
The compound of Formula (5.5.17) was prepared in a manner analogous to that described in Example 14, substituting (R)-2-[3-fluoro-4-({[2-(3-cyano-phenoxy)-pyridine-3-carbonyl]-amino}-methyl)-phenoxy]-propionic acid for the corresponding (R)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid material.
출처 및 근거
- ORD 기록
- ord-45b1100cbf11466dbac1a1cfdfb7df83
- 출처 데이터셋
- uspto-grants-2007_02
- 특허 번호
- US07183293B2
연결된 노트
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