3-Chloro-4-fluorobenzenesulphonyl chloride → HCID 178513461, 화합물

반응식

Cl.[Cl:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH2:9])=[NH:8])=[CH:5][CH:4]=1.[Cl:12][C:13]1[CH:14]=[C:15]([S:20](Cl)(=[O:22])=[O:21])[CH:16]=[CH:17][C:18]=1[F:19]>>[Cl:12][C:13]1[CH:14]=[C:15]([S:20]([NH:8][C:7](=[NH:9])[C:6]2[CH:10]=[CH:11][C:3]([Cl:2])=[CH:4][CH:5]=2)(=[O:21])=[O:22])[CH:16]=[CH:17][C:18]=1[F:19]

참가 물질

반응물 2

HCID 1452223-Chloro-4-fluorobenzenesulphonyl chloride

HCID 2034364-Chlorobenzene-1-carboximidamide hydrochloride

생성물 1

HCID 178513461HCID 178513461, 화합물

실험 절차

4-chlorobenzamidine hydrochloride (0.025 g, 0.133 mmol) and 3-chloro-4 fluorophenyl sulfonylchloride (0.0304 g, 0.133 mmol); were used essentially as described in Example 114 to prepare the title compound. ES Positive Ion MS [M+H]+ ions observed: m/z 347 (35Cl, 35Cl), m/z 349 (37Cl, 37Cl) and m/z 351 (37Cl, 37Cl).

출처 및 근거

ORD 기록: ord-de2086c618724f19854538d46869cde7
출처 데이터셋: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07183320B2

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