Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Methyl-1,2,3,4-tetrahydroquinoline → 6-Methyl-1-(2-nitrophenyl)-1,2,3,4-tetrahydroquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Methyl-1,2,3,4-tetrahydroquinoline | HCID 66678 | — |
| 반응물 | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| 반응물 | 9-Flouro-6-(4-methyl-1-piperazinyl)-1,2-dihydrobenzo[b]pyrrolo[3,2,1-jk][1,4]benzodiazepine | HCID 13823288 | — |
| 생성물 | 6-Methyl-1-(2-nitrophenyl)-1,2,3,4-tetrahydroquinoline | HCID 21297656 | — |
반응 단계
Starting with 6-methyl-1,2,3,4-tetrahydroquinoline and 2-fluoronitrobenzene and following steps 1a to 1f of Example 2, one may obtain, in sequence, 6-methyl-1-(2-nitrophenyl)-1,2,3,4 -tetrahydroquinoline, 1-(2-aminophenyl)-6-methyl-1,2,3,4-tetratetrahydroquinol. 1-(2-aminophenyl)-6-methyl-1,2,3,4-tetrahydroquinoline N-[2-(6-methyl-1-phenyl)-1,2,3,4-tetrahydrohydroquinoline, -1-yl]-4-methyl-1-piperazine carboxamide, and 5-methyl-7-(4-methyl-1-piperazinyl)-2,3-dihydro-1H-quino[18-ab][1,5]-benzodiazepine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04764616 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-dbe5321eb77b4543812282c9e8bf891a |
| 출처 메모 | uspto-grants-1988_08 |