Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetoacetic Acid → Atorvastatin lactone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetoacetic Acid | HCID 96 | — |
| 반응물 | Ethyl Acetoacetate | HCID 8868 | — |
| 반응물 | 7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-3,5-dioxo-heptanoic acid, ethyl ester | HCID 11330705 | — |
| 생성물 | Atorvastatin lactone | HCID 6483036 | — |
반응 단계
In a process analogous to Step 5 METHOD A, by substituting the appropriate ester or amide of acetoacetic acid for ethyl acetoacetate, one obtains the following compounds:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07183408B2 |
| 출처 데이터셋 | uspto-grants-2007_02 |
| ORD ID | ord-366f902b373f4b91ab431912b2e6de22 |
| 출처 메모 | uspto-grants-2007_02 |