Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Bromoquinoline → n-Isopropyl-1-[3-(3-quinolinylethynyl)phenyl]-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Bromoquinoline | HCID 21413 | — |
| 반응물 | 3-Hydroxy-3-phenyl-1-butyne | HCID 92098 | — |
| 반응물 | 1-(3-bromophenyl)-N-isopropyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide | HCID 12991318 | — |
| 생성물 | n-Isopropyl-1-[3-(3-quinolinylethynyl)phenyl]-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide | HCID 10226356 | — |
반응 단계
Following the procedure of EXAMPLE 15, but substituting N-isopropyl-1-(3-ethynylphenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide from Step 2 of EXAMPLE 5 for 2-phenyl-3-butyn-2-ol, and 3-bromoquinoline for N-isopropyl-1-(3-bromophenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide, the title compound was obtained as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06743802B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-058daf43f4e44aa88f5ef26b42ef0cd2 |
| 출처 메모 | uspto-grants-2004_06 |