Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Hydroxy-3-phenyl-1-butyne → HCID 10206059, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Hydroxy-3-phenyl-1-butyne | HCID 92098 | — |
| 반응물 | 1-(3-bromophenyl)-N-isopropyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide | HCID 12991318 | — |
| 반응물 | HCID 22714291 | HCID 22714291 | — |
| 생성물 | HCID 10206059 | HCID 10206059 | — |
반응 단계
Following the procedure of EXAMPLE 15, but substituting N-cyclopropyl-1-(3-ethynylphenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide from EXAMPLE 6 for 2-phenyl-3-butyn-2-ol and 5-bromo-2-(1-hydroxy-1-methylethyl)pyridine-N-oxide from present Step 1 for N-isopropyl-1-(3-bromophenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide, the N-cyclopropyl-1-{3-[6-(1-hydroxy-1-methylethyl)-1-oxido-3-pyridinylethynyl]phenyl}-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide compound was obtained as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06743802B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-b91a2ce40fc4409d9fb0abec3b010979 |
| 출처 메모 | uspto-grants-2004_06 |