Sodium Bicarbonate → HCID 23700750, 화합물

HRID 35197노트

반응식

HRID 35197 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([C:18]([OH:20])=[O:19])[CH:14]=3)[CH:9]=2)[CH:2]=1.C(=O)(O)[O-].[Na+:25]>CO.O>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]2[CH:17]=[CH:16][C:15]3[C:10](=[CH:11][CH:12]=[C:13]([C:18]([O-:20])=[O:19])[CH:14]=3)[CH:9]=2)[CH:2]=1.[Na+:25]

참가 물질

5

반응물 2

HCID 516892Sodium BicarbonateHCID 15612245HCID 15612245, 화합물

생성물 1

HCID 23700750HCID 23700750, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

2-(3-pyridylmethyl)naphthalene-6-carboxylic acid is dissolved in methanol and to this solution a stoichiometric amount of sodium bicarbonate dissolved in water is added. The mixture is stirred at room temperature for one hour, azeotroped with benzene twice and dried under high vacuum for 3 hours. The solid material is recrystallized from methanol and diethyl ether mixture and dried in vacuum at room temperature overnight to give sodium 2-(3-pyridylmethyl)naphthalene-6-carboxylate.

후처리

  1. additionis added
  2. customazeotroped with benzene twice
  3. customdried under high vacuum for 3 hours
  4. customThe solid material is recrystallized from methanol and diethyl ether mixture
  5. customdried in vacuum at room temperature overnight

출처 및 근거

ORD 기록
ord-e4051285d2034c3fab13d34eea952d49
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04766127

반응 노트

불러오는 중…