4-Chloro-2-hydroxybenzonitrile → [4-(5-Chloro-2-cyanophenoxy)-4-(2-methoxy-3-pyridinyl)butyl]carbamic acid 1,1-dimethylethyl ester

HRID 352138노트

반응식

HRID 352138 반응식
[CH3:1][C:2]([O:5][C:6](=[O:21])[NH:7][CH2:8][CH2:9][CH2:10][CH:11]([OH:20])[C:12]1[C:13]([O:18][CH3:19])=[N:14][CH:15]=[CH:16][CH:17]=1)([CH3:4])[CH3:3].[Cl:22][C:23]1[CH:30]=[CH:29][C:26]([C:27]#[N:28])=[C:25](O)[CH:24]=1>>[CH3:4][C:2]([O:5][C:6](=[O:21])[NH:7][CH2:8][CH2:9][CH2:10][CH:11]([O:20][C:29]1[CH:30]=[C:23]([Cl:22])[CH:24]=[CH:25][C:26]=1[C:27]#[N:28])[C:12]1[C:13]([O:18][CH3:19])=[N:14][CH:15]=[CH:16][CH:17]=1)([CH3:1])[CH3:3]

참가 물질

3

반응물 2

HCID 34427894-Chloro-2-hydroxybenzonitrileHCID 131724445[4-Hydroxy-4-(2-methoxy-3-pyridinyl)butyl]carbamic acid 1,1-dimethylethyl ester

생성물 1

HCID 131724446[4-(5-Chloro-2-cyanophenoxy)-4-(2-methoxy-3-pyridinyl)butyl]carbamic acid 1,1-dimethylethyl ester

실험 절차

The sub-title compound was prepared by the method of Example 1 step (b) using the product of step (b) above and 4-chloro-2-hydroxybenzonitrile.

출처 및 근거

ORD 기록
ord-7b24bacd93774db681516064a0623a64
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06743939B2

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