Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Hydroxyproline → 1-(Phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Hydroxyproline | HCID 5810 | — |
| 반응물 | Benzyl chloroformate | HCID 10387 | — |
| 생성물 | 1-(Phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate | HCID 391517 | 58% |
반응 단계
According to the literature procedure (J. Am. Chem. Soc. 189 (1957)), trans-4-hydroxy-L-proline (5.12 g, 0.039 mol) was treated with benzyl chloroformate (8.5 mL, 0.06 mol) to provide the title compound (6.0 g) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06747150B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-ef7a14e3470d461fb1641c7dd5af6295 |
| 출처 메모 | uspto-grants-2004_06 |