Carbon Dioxide → HCID 23688411, 화합물

HRID 352891노트

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HRID 352891 반응식
[N:1]1[C:5]2[CH2:6][CH2:7][O:8][CH2:9][C:4]=2[S:3][CH:2]=1.C([Li:14])CCC.[C:15](=[O:17])=[O:16]>CCOCC>[N:1]1[C:5]2[CH2:6][CH2:7][O:8][CH2:9][C:4]=2[S:3][C:2]=1[C:15]([O-:17])=[O:16].[Li+:14]

참가 물질

5

반응물 3

HCID 280Carbon DioxideHCID 227102096,7-dihydro-4H-pyrano[4,3-d]thiazoleHCID 178418339Butyllithium

생성물 1

HCID 23688411HCID 23688411, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

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온도
-78 °C

실험 절차

In a 200-mL three-necked flask, 4,5-dihydro-7H-pyrano[4,3-d]thiazole (1.14 g) was added and dissolved in ether (30 mL). After cooling to −78° C., 1.6M butyl lithium (6.6 mL) was added and the resulting mixture was stirred. After 20 minutes, a carbon dioxide gas was introduced. After about 15 minutes, the introduction was terminated. The reaction mixture was allowed to rise back to room temperature and concentrated under reduced pressure, whereby the title compound (1.65 g) was obtained as a colorless amorphous substance.

후처리

  1. waitAfter about 15 minutes
  2. customthe introduction was terminated
  3. customto rise back to room temperature
  4. concentrationconcentrated under reduced pressure, whereby the title compound (1.65 g)
  5. customwas obtained as a colorless amorphous substance

출처 및 근거

ORD 기록
ord-fcb15ea9db4749e5a26354b3dc22d89a
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06747023B1

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