1-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride → HCID 178479114, 화합물

반응식

Cl.[NH2:2][C:3]1[NH:4][CH:5]=[C:6]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][CH:9]=2)[N:7]=1.Cl.[Cl:18][C:19]1[CH:20]=[C:21]2[C:26](=[CH:27][CH:28]=1)[CH:25]=[C:24]([S:29]([N:32]1[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1)(=[O:31])=[O:30])[CH:23]=[CH:22]2>>[ClH:18].[NH2:2][C:3]1[NH:4][CH:5]=[C:6]([C:8]2[CH:9]=[CH:10][C:11]([C:12]([N:35]3[CH2:34][CH2:33][N:32]([S:29]([C:24]4[CH:23]=[CH:22][C:21]5[C:26](=[CH:27][CH:28]=[C:19]([Cl:18])[CH:20]=5)[CH:25]=4)(=[O:31])=[O:30])[CH2:37][CH2:36]3)=[O:14])=[CH:15][CH:16]=2)[N:7]=1

참가 물질

반응물 2

HCID 227097661-(6-Chloronaphth-2-ylsulphonyl)piperazine hydrochloride

HCID 178479115HCID 178479115, 화합물

생성물 1

HCID 178479114HCID 178479114, 화합물

실험 절차

In the same manner as in Example A-4, a reaction was conducted using 4-[2-aminoimidazol-4-yl]benzoic acid hydrochloride and 1-[(6-chloronaphthalen-2-yl)sulfonyl]piperazine hydrochloride as starting materials, whereby the title compound was obtained.

출처 및 근거

ORD 기록: ord-6887473624564383a04a5c8d3df3fb5c
출처 데이터셋: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06747023B1

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