1-[(E)-4-Chlorostyrylsulfonyl)piperazine hydrochloride → 1-[(E)-4-Chlorostyrylsulfonyl]-4-[4-(2,4-diaminopyrimidin-6-yl)benzoyl]piperazine Hydrochloride
반응식
Cl.[NH2:2][C:3]1[N:8]=[C:7]([NH2:9])[CH:6]=[C:5]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=O)=[CH:12][CH:11]=2)[N:4]=1.Cl.[Cl:20][C:21]1[CH:37]=[CH:36][C:24](/[CH:25]=[CH:26]/[S:27]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)(=[O:29])=[O:28])=[CH:23][CH:22]=1>>[ClH:20].[Cl:20][C:21]1[CH:22]=[CH:23][C:24](/[CH:25]=[CH:26]/[S:27]([N:30]2[CH2:35][CH2:34][N:33]([C:14](=[O:16])[C:13]3[CH:12]=[CH:11][C:10]([C:5]4[N:4]=[C:3]([NH2:2])[N:8]=[C:7]([NH2:9])[CH:6]=4)=[CH:18][CH:17]=3)[CH2:32][CH2:31]2)(=[O:28])=[O:29])=[CH:36][CH:37]=1참가 물질
3
실험 절차
In the same manner as in Example A-21, a reaction was conducted using 4-(2,4-diamino-6-pyrimidyl)benzoic acid hydrochloride and 1-[(E)-4-chlorostyrylsulfonyl)piperazine hydrochloride obtained in Referential Example 31 as starting materials, whereby the title compound was obtained.
후처리
- customobtained in Referential Example 31