1-[(E)-4-Chlorostyrylsulfonyl)piperazine hydrochloride → 1-[(E)-4-Chlorostyrylsulfonyl]-4-[4-(pyridin-3-yl)benzoyl]piperazine Hydrochloride
반응식
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][CH:9]=2)[CH:3]=1.Cl.[Cl:18][C:19]1[CH:35]=[CH:34][C:22](/[CH:23]=[CH:24]/[S:25]([N:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)(=[O:27])=[O:26])=[CH:21][CH:20]=1>>[ClH:18].[Cl:18][C:19]1[CH:20]=[CH:21][C:22](/[CH:23]=[CH:24]/[S:25]([N:28]2[CH2:33][CH2:32][N:31]([C:12](=[O:14])[C:11]3[CH:10]=[CH:9][C:8]([C:4]4[CH:3]=[N:2][CH:7]=[CH:6][CH:5]=4)=[CH:16][CH:15]=3)[CH2:30][CH2:29]2)(=[O:26])=[O:27])=[CH:34][CH:35]=1참가 물질
3
실험 절차
In the same manner as in Example A-17 except for the use, as starting materials, of 4-(3-pyridyl)benzoic acid hydrochloride and 1-[(E)-4-chlorostyrylsulfonyl]piperazine hydrochloride, a reaction was conducted, whereby the title compound was obtained.
출처 및 근거
- ORD 기록
- ord-0fea678e85e040528a6f4c3d8718a380
- 출처 데이터셋
- uspto-grants-2004_06