Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanolamine → N-(2-Hydroxyethyl)pyrazine-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | Methyl pyrazinoate | HCID 72662 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | N-(2-Hydroxyethyl)pyrazine-2-carboxamide | HCID 14230272 | 80% |
반응 단계
A mixture of 55.2 parts of methyl 2-pyrazinecarboxylate, 48.9 parts of 2-aminoethanol and 360 parts of ethyl acetate was allowed to stand overnight at room temperature. The precipitated product was filtered off, washed with ethyl acetate and dried, yielding 54.5 parts (80%) of N-(2-hydroxyethyl)-2-pyrazinecarboxamide; mp. 125° C. (intermediate 22).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766125 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-5c89f624e3c24f21936bf0d2ca764d41 |
| 출처 메모 | uspto-grants-1988_08 |