Methylamine → 10-(Hydroxymethyl)-9-((methylimino)methyl)anthracene

HRID 353315

반응식

HRID 353315 반응식
[OH:1][CH2:2][C:3]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:10]([CH:17]=O)=[C:9]2[C:4]=1[CH:5]=[CH:6][CH:7]=[CH:8]2.[CH3:19][NH2:20]>CO>[OH:1][CH2:2][C:3]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:10]([CH:17]=[N:20][CH3:19])=[C:9]2[C:4]=1[CH:5]=[CH:6][CH:7]=[CH:8]2

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 376503610-(Hydroxymethyl)anthracene-9-carbaldehyde

생성물 1

HCID 2266220010-(Hydroxymethyl)-9-((methylimino)methyl)anthracene

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

10-(hydroxymethyl)-9-anthraldehyde (3.00 g, 12.7 mmol) was added to 50 mL of a saturated solution of methylamine in methanol and stirred at room temperature for 2 h. The solvent and excess methylamine was removed under reduced pressure to afford the imine as a bright yellow powder (quant); 1H NMR (300.13 MHz, DMSO-d6)δ3.35 (s, 3H), 5.51 (s, 2H), 7.61 (m, 4H), 8.55 (m, 4H), 9.48 (s, 1 H).

후처리

  1. customThe solvent and excess methylamine was removed under reduced pressure

출처 및 근거

ORD 기록
ord-b2e4268614104d078e002b0575ddd2d7
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06750311B1

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