Guanidine → HCID 178513081, 화합물

HRID 353445노트

반응식

HRID 353445 반응식
[CH:1]1([C:4]2[N:8]([C:9]3[CH:14]=[CH:13][C:12](S(C)(=O)=O)=[CH:11][C:10]=3Cl)[N:7]=[CH:6][C:5]=2[C:20]([OH:22])=O)[CH2:3][CH2:2]1.[NH2:23][C:24]([NH2:26])=[NH:25]>>[CH:1]1([C:4]2[N:8]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]4[C:10]=3[CH:4]=[CH:5][CH:6]=[N:7]4)[N:7]=[CH:6][C:5]=2[C:20]([NH:25][C:24]([NH2:26])=[NH:23])=[O:22])[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 3520GuanidineHCID 222679905-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid

생성물 1

HCID 178513081HCID 178513081, 화합물

실험 절차

coupling said 5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid with guanidine to form N-(5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine.

출처 및 근거

ORD 기록
ord-f8263021edaf4610967742b9eb181064
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06753334B2

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