Cyclohexaneacetic acid → Cyclohexylacetyl chloride

HRID 35372

반응식

HRID 35372 반응식
[CH:1]1([CH2:7][C:8]([OH:10])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O=S(Cl)[Cl:13]>>[CH:1]1([CH2:7][C:8]([Cl:13])=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 21363Cyclohexaneacetic acidHCID 24386Thionyl Chloride

생성물 1

HCID 2757989Cyclohexylacetyl chloride

실험 절차

Cyclohexyl acetic acid (2.5 g; 0.02 moles) was mixed with SOCl2 (3.7 cc; 0.05 moles) and the resulting solution was kept at 80° C. for 1.5 hours. The mixture was concentrated under vacuum and some washings were carried out with anhydrous toluene to remove SOCl2. The mixture was then dried under vacuum and the title product was obtained as a raw material which was used as such in the next step (b).

후처리

  1. concentrationThe mixture was concentrated under vacuum
  2. customto remove SOCl2
  3. customThe mixture was then dried under vacuum

출처 및 근거

ORD 기록
ord-469fa4391bba411b95e3dae68edade96
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04766222

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