Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
DL-Carnitine → 4-Carbomethoxy butyryl carnitine chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | DL-Carnitine | HCID 288 | — |
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Methyl 4-chloroformylbutyrate | HCID 73916 | — |
| 용매 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | 4-Carbomethoxy butyryl carnitine chloride | HCID 131715702 | — |
반응 단계
To a solution of carnitine chloride (2.0 g; 10 m moles) in TFA (5 cc), 4-carbomethoxy butyryl chloride (1.65 cc; 12 m moles) was added and the resulting reaction mixture was kept at room temperature under stirring for 24 hours. To this mixture anhydrous ethyl ether was then added. A solid formed which was filtered off and crystallized from hot isopropanol. M.P. 130°-132° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766222 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-96f8a0ff3c6b4f4ea6fcbcff987e883e |
| 출처 메모 | uspto-grants-1988_08 |