Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Silica → Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Silica | HCID 24261 | — |
| 반응물 | Fluorosulfuric acid | HCID 24603 | — |
| 반응물 | 1-Chloromethoxy-1,1-difluoro-2-trifluoromethyl-3,3,3-trifluoropropane | HCID 13827695 | — |
| 생성물 | Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate | HCID 13954659 | — |
반응 단계
In a four necked 1 liter flask equipped with a thermometer, a condenser and a stirrer, 1-chloromethoxy-1,1-difluoro-2-trifluoromethyl-3,3,3-trifluoropropane (276.6 g, 1.04 mol), silicon dioxide and fluorosulfuric acid (70.0 g, 0.70 mol) were charged. The reaction was continued at 110° C. for 21 hours. Then, the reaction mixture was distilled to give monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate (190.3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766238 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-3e95dee8e9c04b8297e0607bbde36700 |
| 출처 메모 | uspto-grants-1988_08 |