Tributylamine → 3,3,3-Trifluoro-2-(trifluoromethyl)-1-propene
반응식
C(N(CCCC)CCCC)CCC.[F:14][C:15]([F:27])([F:26])[CH:16]([C:22]([F:25])([F:24])[F:23])[C:17](OCCl)=O>>[F:14][C:15]([F:27])([F:26])[C:16]([C:22]([F:25])([F:24])[F:23])=[CH2:17]참가 물질
3
반응 조건
- 온도
- 65 °C
실험 절차
In a four necked 100 ml flask equipped with a condenser, a dropping funnel and a thermometer, tributylamine (20.0 g, 108 mmoles) was charged and warmed to 65° C. Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate (4.88 g, 20 mmol) was dropwise added thereto while stirring. The reaction was continued at the same temperature as above for 3 hours while stirring. The gas evolved from a top of the condenser was washed with an alkaline solution, dried with alumina and cooled. The resultant liquid was distilled to give 2-trifluoromethyl-3,3,3-trifluoropropene (2.49 g). Yield, 76 %.
후처리
- customIn a four necked 100 ml flask equipped with a condenser, a dropping funnel
- customwas continued at the same temperature as above for 3 hours
- stirringwhile stirring
- washwas washed with an alkaline solution
- customdried with alumina
- temperaturecooled
- distillationThe resultant liquid was distilled
출처 및 근거
- ORD 기록
- ord-d57e115760924d43a21fc3df3125c5f3
- 출처 데이터셋
- uspto-grants-1988_08
- 특허 번호
- US04766238
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