Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methylol-alpha-chloroacetamide → 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methylol-alpha-chloroacetamide | HCID 62466 | — |
| 반응물 | 4-(1,1-Dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol | HCID 54155563 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 2-Chloro-N-[5-(1,1-dimethylethyl)-3-dimethylaminomethyleneaminosulfonyl-2-hydroxybenzyl]-acetamide | HCID 53948117 | — |
반응 단계
3 g (0.01 mole) of 4-(1,1-dimethylethyl)-2-dimethylaminomethyleneaminosulfonylphenol are dissolved in 30 ml of sulfuric acid, and 1.1 g (0.009 mole) of 2-chloro-N-hydroxymethylacetamide are added. The mixture is stirred for 30 minutes at room temperature and poured into ice water. The product is filtered off with suction and recrystallized from methanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766241 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-aef4cd9e4021414984007a97f385e38f |
| 출처 메모 | uspto-grants-1988_08 |