Diethylcarbamoyl chloride → N,N-Diethyl carbamoyl thiocyanate

HRID 353982

반응식

HRID 353982 반응식
[S-:1][C:2]#[N:3].[Na+].[CH2:5]([N:7]([CH2:11][CH3:12])[C:8](Cl)=[O:9])[CH3:6]>C(#N)C>[CH2:5]([N:7]([CH2:11][CH3:12])[C:8]([S:1][C:2]#[N:3])=[O:9])[CH3:6]

참가 물질

4

반응물 2

HCID 6916Diethylcarbamoyl chlorideHCID 516871Sodium thiocyanate

생성물 1

HCID 22063149N,N-Diethyl carbamoyl thiocyanate

시약·촉매·용매 1

HCID 6342Acetonitrile용매2회

반응 조건

온도
80 °C

실험 절차

A suspension of sodium thiocyanate (3.30 g, 40.7 mmol) in dry acetonitrile (25 mL) at 80° C. was treated dropwise with a solution of N,N-diethyl carbamoyl chloride (5.0 g, 36.9 mmol) in dry acetonitrile (15 mL). The reaction mixture was stirred at 80° C. for 50 min, cooled to room temperature, then filtered through a fine glass frit. The resulting filtrate was used as a 0.9 M solution of N,N-diethyl carbamoyl thiocyanate in acetonitrile.

후처리

  1. temperaturecooled to room temperature
  2. filtrationfiltered through a fine glass frit

출처 및 근거

ORD 기록
ord-fc4f44047e62413988f74e10ccb54b5a
출처 데이터셋
uspto-grants-2004_06
특허 번호
US06756372B2

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