Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → N-[(5-tert-Butyl-2-hydroxyphenyl)methyl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | 2-(Aminomethyl)-4-tert-butylphenol hydrochloride | HCID 21296950 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | N-[(5-tert-Butyl-2-hydroxyphenyl)methyl]acetamide | HCID 13210348 | — |
반응 단계
43 g (0.2 mole) of 2-aminomethyl-4-(1,1-dimethylethyl)-phenol hydrochloride are suspended in 400 ml of 1,4-dioxane, and 40 ml of pyridine are added. 40 ml (0.55 mole) of acetyl chloride are added dropwise while stirring and cooling with ice. The mixture is then stirred for 2.5 hours at 90° and poured into ice water, and the precipitate which has crystallized out is filtered off with suction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766241 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-961680e386e54d8096eab17a00cca646 |
| 출처 메모 | uspto-grants-1988_08 |