N-(2-Aminoethyl)piperidine → [6-Methoxy-2-(4-methoxy-phenyl)-benzo[b]thiophen-3-yl]-[6-(2-piperidin-1-yl-ethylamino)-pyridin-3-yl]-methanone
반응식
Cl[C:2]1[N:7]=[CH:6][C:5]([C:8]([C:10]2[C:11]3[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][C:12]=3[S:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[O:9])=[CH:4][CH:3]=1.[NH2:29][CH2:30][CH2:31][N:32]1[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]1>>[CH3:28][O:27][C:24]1[CH:25]=[CH:26][C:11]2[C:10]([C:8]([C:5]3[CH:6]=[N:7][C:2]([NH:29][CH2:30][CH2:31][N:32]4[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]4)=[CH:3][CH:4]=3)=[O:9])=[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)[S:13][C:12]=2[CH:23]=1참가 물질
3
실험 절차
The coupling of the product from Step 1, Example 5 (6-Chloro-pyridin-3-yl)-[6-methoxy-2-(4-methoxy-phenyl) -benzo[b]thiophen-3-yl]-methanone) and 1-(2-Aminoethyl)-piperidine was carried out as in Example 5, Step 2 to give the title compound.
출처 및 근거
- ORD 기록
- ord-be74a8820bc049ca8c2666ddf009a282
- 출처 데이터셋