Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chlorosulfonic acid → 6-(N-Chloroacetylaminomethyl)-5-hydroxy-4-chlorosulfonylindane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chlorosulfonic acid | HCID 24638 | — |
| 반응물 | 2-Chloro-N-[(6-hydroxy-2,3-dihydro-1H-inden-5-yl)methyl]acetamide | HCID 21296915 | — |
| 생성물 | 6-(N-Chloroacetylaminomethyl)-5-hydroxy-4-chlorosulfonylindane | HCID 21296931 | — |
반응 단계
70 g (0.29 mole) of 6-(N-chloroacetylaminomethyl)-5-hydroxyindane are dissolved in 150 ml of chlorosulfonic acid, and the mixture is stirred for approx. 30 minutes at room temperature. The mixture is poured into ice water and the product is filtered off with suction. The initially crystalline material becomes oily after a little time and is employed in the next stage in this form without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766241 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-602c8eb7a33141f29baf3356b4e49d0a |
| 출처 메모 | uspto-grants-1988_08 |