참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 3-Aminophenol | HCID 11568 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Hydroxyacetanilide | HCID 12124 | 89.3% |
반응 단계
To a stirred solution of 66.0 g (0.60 mole) of 3-aminophenol in 180 mL of water was added dropwise 77.9 g (0.76 mole) of acetic anhydride. After complete addition, the reaction mixture was heated on a steam bath for 10 minutes, then cooled to 0° C. A precipitate formed and was collected by filtration. The filter cake was washed with cold water and dried in a desiccator for two hours to yield 81.0 g of 3-hydroxyacetanilide (mp 144°-146° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04766233 |
|---|
| 출처 데이터셋 | uspto-grants-1988_08 |
|---|
| ORD ID | ord-942e1905c51f4c43895ec9e90acc6ad0 |
|---|
| 출처 메모 | uspto-grants-1988_08 |
|---|
