Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chloro-2-methylanisole → 3-Chloro-o-cresol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chloro-2-methylanisole | HCID 76749 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 3-Chloro-o-cresol | HCID 14856 | — |
반응 단계
3.1 g (0.02 mol) of 3-chloro-2-methylanisole are heated in 20 ml of 50% sulphuric acid for 18 hours with reflux. After cooling, the reaction mixture is extracted three times with dichloromethane, dried over sodium sulphate and concentrated to dryness under reduced pressure. 3-Chloro-2-methylphenol is obtained as a solid (2.9 g, content by HPLC: 11.7%, 12% of theory).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06756512B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-4f149bc2b5f84728ba42e39fa0b4c854 |
| 출처 메모 | uspto-grants-2004_06 |