Water → HCID 13135248, 화합물
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[C:1]([C:3]1[C:4]([CH3:13])=[C:5]([C:9]([CH3:12])=[CH:10][CH:11]=1)[C:6](O)=[O:7])#[N:2].B.O.C(=O)([O-])[O-].[K+].[K+]>O1CCCC1>[C:1]([C:3]1[C:4]([CH3:13])=[C:5]([CH2:6][OH:7])[C:9]([CH3:12])=[CH:10][CH:11]=1)#[N:2]참가 물질
6
실험 절차
A solution of 3-cyano-2,6-dimethylbenzoic acid (8.11 grams, 0.049 mole) in tetrahydrofuran (100 ml) was cooled to 0°. Borane (48.7 grams, 0.049 mole) in tetrahydrofuran was added dropwise over a 20 minute period. The mixture was allowed to come to room temperature, and water was added. Potassium carbonate was added to separate the layers. The aqueous layer was extracted with diethyl ether. The extract was added to the organic phase, which was dried over magnesium sulfate, filtered, and the solvent evaporated to give (3-cyano-2,6-dimethylphenyl)methanol (2.93 grams).
후처리
- customto come to room temperature
- customto separate the layers
- extractionThe aqueous layer was extracted with diethyl ether
- additionThe extract was added to the organic phase, which
- dry with materialwas dried over magnesium sulfate
- filtrationfiltered
- customthe solvent evaporated
출처 및 근거
- ORD 기록
- ord-b4710c02690841ae94fc02b6b2f138f5
- 출처 데이터셋
- uspto-grants-1983_03
- 특허 번호
- US04375476
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