Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 1-(2-Benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Propyl mercaptan | HCID 7848 | — |
| 반응물 | Timoprazole | HCID 72171 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-(2-Benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride | HCID 21295953 | — |
반응 단계
2.6 g of 2-[(2-pyridylmethyl)sulphinyl]benzimidazole are dissolved in 30 ml of tetrahydrofuran and treated with 1.0 ml of n-propyl mercaptan. 10 ml of 3N hydrochloric acid are added at an internal temperature of 40°. The mixture is stirred at 40° for 5 minutes and then evaporated in vacuo. The residue is crystallized from ethanol/ether. There is obtained 1-(2-benzimidazolyl)-2-[(propyldithio)methyl]pyridinium chloride of melting point 144°-145°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04766133 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-fa30a22ce0ca4274b65e81863b1b0172 |
| 출처 메모 | uspto-grants-1988_08 |