(1,4-Diazepan-1-yl)(furan-2-yl)methanone → 1-(Tetrahydrofuran-2-ylcarbonyl)-1,4-diazepane
반응식
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7]>[Rh].C(O)C>[O:1]1[CH2:5][CH2:4][CH2:3][CH:2]1[C:6]([N:8]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=[O:7]참가 물질
4
실험 절차
N-(2-Furoyl)homopiperazine (33.0 g.) in 200 ml. of ethanol was hydrogenated over 5% rhodium-on-carbon catalyst at three atmospheres pressure. The catalyst was removed by filtration and the product distilled to give the desired product, B.P. 135° at 1 mm.
후처리
- customThe catalyst was removed by filtration
- distillationthe product distilled
출처 및 근거
- ORD 기록
- ord-52064a5f0b7744a1bfc854a0c8935f0d
- 출처 데이터셋
- uspto-grants-1983_03
- 특허 번호
- US04377581
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