Salicylic Acid → 5-(2-Propylpentanoyl)Salicylic Acid

반응식

[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:11]([CH:14]([CH2:18][CH2:19][CH3:20])[C:15](Cl)=[O:16])[CH2:12][CH3:13]>>[CH2:11]([CH:14]([CH2:18][CH2:19][CH3:20])[C:15]([C:7]1[CH:8]=[C:2]([C:1]([OH:10])=[O:9])[C:3]([OH:4])=[CH:5][CH:6]=1)=[O:16])[CH2:12][CH3:13]

참가 물질

반응물 2

HCID 338Salicylic Acid

HCID 762402-Propylvaleryl chloride

생성물 1

HCID 137487105-(2-Propylpentanoyl)Salicylic Acid수율 52%

실험 절차

This compound is prepared by a Friedel-Crafts reaction from salicylic acid and 2-propylpentanoyl chloride. The acid yield is 52%. The recrystallization is done in petroleum ether. The melting point is 118° C.

후처리

customThe recrystallization

출처 및 근거

ORD 기록: ord-6261f72d624144a1932153c5569dbb6b
출처 데이터셋: uspto-grants-1988_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04767750

반응 노트

불러오는 중…