ethyl 2-((E)-4-methoxybenzylidene)butyrate → HCID 14329809, 화합물

HRID 35577노트

반응식

HRID 35577 반응식
[H-].[Al+3].[Li+].[H-].[H-].[H-].[CH3:7][O:8][C:9]1[CH:23]=[CH:22][C:12](/[CH:13]=[C:14](\[CH2:20][CH3:21])/[C:15](OCC)=[O:16])=[CH:11][CH:10]=1>CCOCC>[CH3:7][O:8][C:9]1[CH:23]=[CH:22][C:12](/[CH:13]=[C:14](\[CH2:20][CH3:21])/[CH2:15][OH:16])=[CH:11][CH:10]=1

참가 물질

4

반응물 2

HCID 10933410ethyl 2-((E)-4-methoxybenzylidene)butyrateHCID 21226445Aluminium lithium hydride2회

생성물 1

HCID 14329809HCID 14329809, 화합물수율 83.4%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매3회

실험 절차

To a suspension of lithium aluminum hydride (3 g) in dry ether (300 ml) was added a solution of ethyl 2-((E)-4-methoxybenzylidene)butyrate (19 g) in dry ether (30 ml) at 0° C. with stirring. The mixture was stirred at the same temperature for 3 hours and excess lithium aluminum hydride was decomposed with wet ether. The reaction mixture was filtered and the filtrate was washed with water, dried over magnesium sulfate and then evaporated to dryness to give 2-((E)-4-methoxybenzylidene)butan-1-ol (13 g).

후처리

  1. stirringThe mixture was stirred at the same temperature for 3 hours
  2. filtrationThe reaction mixture was filtered
  3. washthe filtrate was washed with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated to dryness

출처 및 근거

ORD 기록
ord-c2a023fb300944d39deb4e99c77ecce6
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04767768

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