Chlorine → 2-Chloro-5H-dibenzo[b,e]azepine-6,11-dione
반응식
[Cl:1]Cl.[CH:3]1[C:13]2[C:12](=[O:14])[C:11]3[CH:15]=[CH:16][CH:17]=[CH:18][C:10]=3[C:9](=[O:19])[NH:8][C:7]=2[CH:6]=[CH:5][CH:4]=1>C(O)(=O)C>[Cl:1][C:4]1[CH:5]=[CH:6][C:7]2[NH:8][C:9](=[O:19])[C:10]3[CH:18]=[CH:17][CH:16]=[CH:15][C:11]=3[C:12](=[O:14])[C:13]=2[CH:3]=1참가 물질
4
실험 절차
Chlorine gas is bubbled into a mixture (partial suspension) of 1.0 g (450 mmol) of 5H-dibenz[b,e]azepine-6,11-dione in 50 ml of glacial acetic acid. The temperature of the mixture rises to 38° C. On standing, as the temperature of the solutions decreases, a white solid precipitates. The mixture is filtered to give 0.40 g of solid (mixture of starting material and product in ratio of 1:8). The filtrate on standing gives 0.10 g of product as crystals, m.p. 289°-293° C.
후처리
- customrises to 38° C
- customa white solid precipitates
- filtrationThe mixture is filtered
출처 및 근거
- ORD 기록
- ord-fb114cbe284f4bf9ae8ff217a3a146ae
- 출처 데이터셋
- uspto-grants-1998_11
- 특허 번호
- US05834461
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