참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 2,3,4,5-tetrahydro-1H-1-benzazepine-2,5-dione | HCID 369398 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-dimethylaminomethylene-3,4-dihydro-1H-benzo[b]azepine-2,5-dione | HCID 66934763 | 79% |
반응 단계
A mixture of 0.250 g (1.43 mmol) of 3,4-dihydro-1H-1-benzazepine-2,5-dione and 5.5 ml (4.93 g, 41.5 mmol) of N,N-dimethylformamide, dimethylacetal is heated at 90° C. for 1.5 hour. The mixture is cooled, diluted with diethylether and filtered. The solid is washed well with diethylether and dried to give 0.26 g of tan crystals, m.p. 203°-205° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05834461 |
|---|
| 출처 데이터셋 | uspto-grants-1998_11 |
|---|
| ORD ID | ord-38c2e7cb532c46dea5a8d0e551bd2626 |
|---|
| 출처 메모 | uspto-grants-1998_11 |
|---|
