참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 6-Bromohexanenitrile | HCID 81093 | — |
| 반응물 | 1-(3-Hydroxybenzyl)piperidine | HCID 826974 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 6-(3-Piperidinomethylphenoxy)hexanenitrile | HCID 21294599 | — |
반응 단계
N-(3-Hydroxybenzyl)piperidine (9.55 g) was heated with 6-bromohexanenitrile (10.2 g) and potassium carbonate (13.8 g) under reflux in acetone (150 ml) for 66 hours. The reaction mixture was cooled and filtered. The solvent was removed by evaporation and the residue was heated with stirring at 100° C. for one hour to remove unreacted 6-bromohexanenitrile and to yield 6-(3-piperidinomethylphenoxy)hexanenitrile as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04767769 |
|---|
| 출처 데이터셋 | uspto-grants-1988_08 |
|---|
| ORD ID | ord-7da3d269d1874f798df02cc7c96fa40f |
|---|
| 출처 메모 | uspto-grants-1988_08 |
|---|
