1,1-Dibromododecane → 1,1'-(1,12-dodecanediyl)bis(4-(4-methyl-phenyl)-2(1H)-pyridinimine) dihydrobromide

HRID 355944

반응식

HRID 355944 반응식
[Br:1][CH:2](Br)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[NH2:15][C:16]1[CH:21]=[C:20]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)[CH:19]=[CH:18][N:17]=1>>[BrH:1].[BrH:1].[CH2:2]([N:17]1[CH:18]=[CH:19][C:20]([C:22]2[CH:23]=[CH:24][C:25]([CH3:28])=[CH:26][CH:27]=2)=[CH:21][C:16]1=[NH:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N:17]1[CH:18]=[CH:19][C:20]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)=[CH:21][C:16]1=[NH:15]

참가 물질

3

반응물 2

HCID 113249061,1-DibromododecaneHCID 137770672-Amino-4-(4-methylphenyl)pyridine

생성물 1

HCID 676451951,1'-(1,12-dodecanediyl)bis(4-(4-methyl-phenyl)-2(1H)-pyridinimine) dihydrobromide

실험 절차

The procedure is as above, with dibromododecane and 2-amino-4-para-tolylpyridine, which is synthesized according to Chambron J.Cl. Strasbourg Tetrah. 1987 43 (5) 895/905. The product obtained is purified in the base state on a silica column with a benzene/ethyl acetate mixture. It is reconverted to the hydrobromide with a mixture of ether and an isopropanol solution of hydrogen bromide. It can then be recrystallized.

후처리

  1. customis synthesized
  2. customThe product obtained
  3. customis purified in the base state on a silica column with a benzene/ethyl acetate mixture
  4. additionIt is reconverted to the hydrobromide with a mixture of ether
  5. customIt can then be recrystallized

출처 및 근거

ORD 기록
ord-9dada8b2b8234a8b9d4b796da7fd8a1e
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05834491

연결된 노트

불러오는 중…