5-Bromoindole → 5-phenyl-1H-indole

반응식

Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[C:11]1([C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[NH:7][CH:6]=[CH:5]3)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

반응물 2

HCID 249055-Bromoindole

HCID 66827Phenylboronic Acid

생성물 1

HCID 114582105-phenyl-1H-indole수율 87%

실험 절차

The title compound was prepared from 5-bromoindole and benzeneboronic acid by the method of Suzuki (N. Miyaura, T Yanagi, A Suzuki, Synth. Commun, 1981, 513) in 87% yield.

출처 및 근거

ORD 기록: ord-68ffa5406f7f4209841744ce14aa54a3
출처 데이터셋: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05834494

반응 노트

불러오는 중…