Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 5-Nitro-1-(3-pyridylcarbamoyl)indoline Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | 3-Pyridinecarbonyl Azide | HCID 19914 | — |
| 반응물 | 5-Nitroindoline | HCID 36219 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 5-Nitro-1-(3-pyridylcarbamoyl)indoline Hydrochloride | HCID 18940945 | 76% |
반응 단계
This material was prepared from nicotinoyl azide (0.43 g, 2.9 mmol) and 5-nitroindoline (0.38 g, 2.3 mmol), and conversion of the precipitated urea to the salt using excess HCl in ether, following the procedure of Example 2. This gave the title compound (0.64 g, 76%) as a light yellow powder, m.p. 244°-7° C. (dec.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05834494 |
| 출처 데이터셋 | uspto-grants-1998_11 |
| ORD ID | ord-aafc92b2637a4682a1f40d81e42fab24 |
| 출처 메모 | uspto-grants-1998_11 |