Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(Cyanomethyl)-phthalimide → 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(Cyanomethyl)-phthalimide | HCID 345881 | — |
| 반응물 | Diethyl dithiophosphate, potassium salt | HCID 1385274 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide | HCID 24696128 | — |
반응 단계
In a 20 ml 4N solution of hydrogen chloride in ethyl acetate, 3.07 g of phthalimidoacetonitrile was dissolved. To the resulting solution, 3.17 ml of O,O-diethyl dithiophosphate was added, followed by stirring at room temperature for 6 hours. The precipitate formed was collected by filtration, and washed successively with ethyl acetate and diethyl ether, whereby 2.29 g of phthalimidothioacetamide was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05834499 |
| 출처 데이터셋 | uspto-grants-1998_11 |
| ORD ID | ord-447b185e459e4007afb89349afc2be54 |
| 출처 메모 | uspto-grants-1998_11 |