Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 356160생성일: 2026년 10월 25일
Acetic Anhydride → (3aR*,10aS*)-4-Acetyl-9-benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one
https://huagongshe.com/reaction/356160
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | (3aR*,10aS*)-9-benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta [e][1,4]diazepin-10(1H)-one | HCID 70109795 | — |
| 생성물 | (3aR*,10aS*)-4-Acetyl-9-benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one | HCID 70110285 | 77% |
반응 단계
A mixture of (3aR*,10aS*)-9-benzyl-2,3,3a,4,9,10a-hexahydrobenzo[b]cyclopenta[e][1,4]diazepin-10(1H)-one (1.47 g, 5.0 mmol) and acetic anhydride (5 mL) was stirred for 35 minutes at 100° C. Resulting crystalline precipitate was collected by filtration, which was washed with ethanol to give 1.29 g (yield 77%) of the titled compound, m.p. 209°-210° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US05834463 |
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| 출처 데이터셋 | uspto-grants-1998_11 |
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| ORD ID | ord-964ef6054fd64222a4d6a736aaf7519d |
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| 출처 메모 | uspto-grants-1998_11 |
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