Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-diethyl-m-toluamide → N,N-Diethyl-5-methyl-2-(trimethylsilyl)benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-diethyl-m-toluamide | HCID 4284 | — |
| 반응물 | Chlorotrimethylsilane | HCID 6397 | — |
| 생성물 | N,N-Diethyl-5-methyl-2-(trimethylsilyl)benzamide | HCID 18630275 | 46% |
반응 단계
These compounds were prepared from N,N-diethyl-3-methylbenzamide and 2.0 eq TMSCl according to General Method A. Purification by HPLC using 1:9 ethyl acetate/hexanes gave two products. Compound 63 was isolated as 6.0 g of a clear oil, a 46% yield. Compound 64 was isolated as 2.3 g of a clear oil, a 17% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05834447 |
| 출처 데이터셋 | uspto-grants-1998_11 |
| ORD ID | ord-ce55615b62654e459d205559d0d83700 |
| 출처 메모 | uspto-grants-1998_11 |