1-(4-Hydroxyphenyl)-3-phenylprop-2-en-1-one → HCID 14416163, 화합물

HRID 356459

반응식

HRID 356459 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:17])[CH:9]=[CH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:4][CH:3]=1>[Pd].C1COCC1>[OH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](=[O:17])[CH2:9][CH2:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[CH:6][CH:7]=1

참가 물질

4

반응물 1

HCID 942401-(4-Hydroxyphenyl)-3-phenylprop-2-en-1-one

생성물 1

HCID 14416163HCID 14416163, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8028Tetrahydrofuran용매

실험 절차

The title compound was prepared as described in General Method 3 from 1-(4-hydroxy-phenyl)-3-phenyl-prop-2-en-1-one (16.5 g, 74.0 mmol), 5% Pd on BaSO4 (1.0 g), and THF (400 mL). The product was recrystallized from 50% EtOH to give the title compound, m.p. 102°-105° C. 1H NMR (CDCl3) δ 3.02 (t, 2 H), 3.22 (t, 2 H), 5.83 (s, 1 H), 6.84 (d, 2 H), 7.15-7.28 (m, 5 H), 7.88 (d, 2 H).

후처리

  1. customThe title compound was prepared
  2. customThe product was recrystallized from 50% EtOH

출처 및 근거

ORD 기록
ord-19aebf46a7c94cb19bcc7b8c29794b7e
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05834506

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