Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetradecyltrimethylammonium → 1-(1H-1,2,4-Triazol-1-yl)cyclopropyl 2,4-dichlorophenyl ketone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetradecyltrimethylammonium | HCID 14251 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Sulfoxonium, trimethyl-, iodide (1:1) | HCID 74498 | — |
| 반응물 | 2',4'-Dichloro-2-(1H-1,2,4-triazol-1-yl)prop-2-enophenone | HCID 21294611 | — |
| 용매 | 1,1,1-Trichloroethane | HCID 6278 | — |
| 생성물 | 1-(1H-1,2,4-Triazol-1-yl)cyclopropyl 2,4-dichlorophenyl ketone | HCID 21294612 | — |
반응 단계
2',4'-Dichloro-2-(1H-1,2,4-triazol-1-yl)prop-2-enophenone (0.27 g, 1.0 mMole) was added dropwise in 1,1,1-trichloroethane (2 ml) to a refluxing mixture of trimethylsulphoxonium iodide (0.33 g, 1.5 mMole), cetrimide (0.03 g), 1,1,1-trichloroethane (5 ml) and aqueous 2N sodium hydroxide (3 ml) with vigorous stirring over 2 minutes. After refluxing for a further 15 minutes the organic phase, after cooling was separated. Evaporation gave a gum, weight 0.11 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04767777 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-6c3a4db47a0a45f68dd1d01da747a525 |
| 출처 메모 | uspto-grants-1988_08 |