Triethylamine → 5-(4-Methanesulfonyloxybutyloxy)imidazo[1,2-a]pyridine

HRID 357009노트

반응식

HRID 357009 반응식
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[N:12]2[CH:13]=[CH:14][N:15]=[C:11]2[CH:10]=[CH:9][CH:8]=1.C(N(CC)CC)C.[CH3:23][S:24](Cl)(=[O:26])=[O:25]>>[CH3:23][S:24]([O:1][CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[N:12]2[CH:13]=[CH:14][N:15]=[C:11]2[CH:10]=[CH:9][CH:8]=1)(=[O:26])=[O:25]

참가 물질

4

반응물 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 189368131-Butanol,4-(imidazo[1,2-a]pyridin-5-yloxy)-

생성물 1

HCID 189368245-(4-Methanesulfonyloxybutyloxy)imidazo[1,2-a]pyridine

실험 절차

Using 1.65 g (8.0 mmol) of 5-(4-hydroxybutyloxy)-imidazo[1,2-a]pyridine, 1.23 ml (8.8 mmol) of triethylamine and 0.68 ml (8.8 mmol) of methanesulfonyl chloride, the same procedure as in Reference Example 8 was followed, to yield 5-(4-methanesulfonyloxybutyloxy)imidazo[1,2-a]pyridine.

출처 및 근거

ORD 기록
ord-9f47e1b1164f46d0a177273970736fc3
출처 데이터셋
uspto-grants-1998_11
특허 번호
US05840732

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