5-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-heptene → (3S)-3-Methylheptan-1-OL

HRID 35723노트

반응식

HRID 35723 반응식
[CH3:1][C@H:2]([CH2:7][CH2:8][O:9][Si](C(C)(C)C)(C)C)[CH2:3][CH:4]=[CH:5][CH3:6].[H][H]>[OH-].[OH-].[Pd+2].CO>[CH3:1][C@@H:2]([CH2:3][CH2:4][CH2:5][CH3:6])[CH2:7][CH2:8][OH:9]

참가 물질

5

반응물 2

HCID 537803775-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-hepteneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 12490717(3S)-3-Methylheptan-1-OL

시약·촉매·용매 2

HCID 9942167Palladium hydroxide촉매HCID 887Methanol용매

실험 절차

To a solution of 74.8 g. of 5-(S)-methyl-7-(t-butyldimethylsilyloxy)-2-heptene in 500 ml. of methanol was added 7.5 g. of 10% palladium hydroxide on carbon and the mixture shaken in a hydrogen atmosphere for 1.5 hours at 50 psi. The catalyst was filtered and the solvent removed under vacuum, 30 g.

후처리

  1. filtrationThe catalyst was filtered
  2. customthe solvent removed under vacuum, 30 g

출처 및 근거

ORD 기록
ord-01daf8a69ff143439ee15aa2712ff87a
출처 데이터셋
uspto-grants-1988_08
특허 번호
US04767743

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