Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hexane → 2-Amino-3-hydroxybenzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hexane | HCID 8058 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 3-Hydroxy-2-nitrobenzonitrile | HCID 13862423 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Amino-3-hydroxybenzonitrile | HCID 15906336 | — |
반응 단계
A parr bottle was charged with palladium on activated carbon (5%, 0.196g). A solution of 2-nitro-3-hydroxybenzonitrile (1.31 g, 0.008 mol) in 40 ml of ethanol was added. The reaction mixture was placed under 25 psi of hydrogen gas and shaken for 1 hour. TLC (1:1 hexane:ethyl acetate) shows that no starting material remained. The mixture was filtered through Celite® and evaporated to yield 2-amino-3-hydroxybenzonitrile, 1.01 g (0.0075 mol, 94%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05840764 |
| 출처 데이터셋 | uspto-grants-1998_11 |
| ORD ID | ord-59f4430508a249a3b05078ccf53bc50f |
| 출처 메모 | uspto-grants-1998_11 |