Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Ampicillin Trihydrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ampicillin | HCID 6249 | — |
| 생성물 | Ampicillin Trihydrate | HCID 23565 | — |
반응 단계
The resultant crude protected ampicillin mixture is worked up by treating with a mixture of ice-water and concentrated HCl. After phase separation the aqueous phase is brought to pH 4.5. The title compound is obtained after filtration and washing with 90% aqueous acetone, followed by drying. Yield 66.34 g=89%. Purity 98.8%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05840885 |
| 출처 데이터셋 | uspto-grants-1998_11 |
| ORD ID | ord-1bf74494d5f2409fae1c1286e6520a37 |
| 출처 메모 | uspto-grants-1998_11 |