Sodium Bicarbonate → 2-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-

HRID 358295

반응식

HRID 358295 반응식
O[C:2]1([CH3:11])[CH:6]([CH2:7][CH:8]=[CH2:9])[C:5](=[O:10])[CH:4]=[CH:3]1.C(=O)([O-])[OH:13].[Na+]>>[CH2:7]([C:6]1[C:5](=[O:10])[CH2:4][CH:3]([OH:13])[C:2]=1[CH3:11])[CH:8]=[CH2:9]

참가 물질

3

반응물 2

HCID 516892Sodium BicarbonateHCID 128798724-Hydroxy-4-methyl-5-(prop-2-en-1-yl)cyclopent-2-en-1-one

생성물 1

HCID 110832-Cyclopenten-1-one, 4-hydroxy-3-methyl-2-(2-propen-1-yl)-수율 75%

실험 절차

In 200 ml of a 5% aqueous sodium hydrogencarbonate solution, was dissolved 29 g of 4-hydroxy-4-methyl-5-allyl-2-cyclopentenone. The solution was heated with stirring under reflux for one hour. After having been allowed to cool, the reaction mixture was extracted three times with chloroform. The extract solution was dried over anhydrous magnesium sulfate and freed from the chloroform by distillation. The residue was distilled in vacuo to obtain 21.7 g (75% yield) of 2-allyl-3-methyl-4-hydroxy-2-cyclopentenone boiling at 155° C./1 mmHg.

후처리

  1. temperatureThe solution was heated
  2. temperatureunder reflux for one hour
  3. temperatureto cool
  4. extractionthe reaction mixture was extracted three times with chloroform
  5. dry with materialThe extract solution was dried over anhydrous magnesium sulfate
  6. distillationfreed from the chloroform by distillation
  7. distillationThe residue was distilled in vacuo

출처 및 근거

ORD 기록
ord-cd46fe39913045f795d3913d5218cf2d
출처 데이터셋
uspto-grants-1984_08
특허 번호
US04465862

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