Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Hydroxy-4-methoxybenzophenone → {4-Methoxy-2-[(prop-2-en-1-yl)oxy]phenyl}(phenyl)methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Hydroxy-4-methoxybenzophenone | HCID 4632 | — |
| 반응물 | Potassium Iodide | HCID 4875 | — |
| 반응물 | Allyl chloride | HCID 7850 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | {4-Methoxy-2-[(prop-2-en-1-yl)oxy]phenyl}(phenyl)methanone | HCID 14227056 | — |
반응 단계
2-Hydroxy-4-methoxybenzophenone (114 parts) was dissolved in tetrahydrofuran (100 parts). Potassium hydroxide (30.9 parts) was added. By heating and stirring, complete dissolution was achieved. Allyl chloride (46.4 parts) and potassium iodide (4.2 parts) were added to this solution, which was then heated and refluxed for 8 hours. After cooling, it was washed with water and the solvent was removed by distillation. A crude product of the desired 2-allyloxy-4-methoxybenzophenone was obtained. It was recrystallized in n-hexane to obtain 125 parts of 2-allyloxy-4-methoxybenzophenone (melting point 40° C.) at 93% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04467082 |
| 출처 데이터셋 | uspto-grants-1984_08 |
| ORD ID | ord-b194dbbb179640d88942b8ef085f31a9 |
| 출처 메모 | uspto-grants-1984_08 |